Photochemical Synthesis of Indolocarbazoles through Tandem Indolization/Dimerization/Mannich Cyclization from AllenesBy: Jiaying Tang, Linlin Ren, Jianwei Li, Yonggong Wang, Dongyan Hu, Xiaogang Tong*, and Chengfeng Xia*ORGANIC LETTERS 24（19）：3582-3587DOI：https://doi.org/10.1021/acs.orglett.2c01371Published：MAY 20 2022AbstractIndolocarbazole alkaloids and their derivatives were discovered ...

Hepatic RACK1 deletion disturbs lipid and glucose homeostasis independently of insulin resistance.By: Qin, Wanying; Zhang, Ting; Ge, Mingxia; Zhou, Huimin; Xu, Yuhui; Mu, Rongfang; Huang, Chaoguang; Liu, Daowei; Huang, Bangrui; Wang, Qian; Kong, Qinghua; Kong, Qingpeng; Li, Fei; Xiong, WenyongThe Journal of endocrinologyDOI：https://doi.org/10.1530/JOE-22-0076Published：2022-May-01AbstractRecep...

Strategies for total synthesis of bispyrrolidinoindoline alkaloidsMa, Zhixian; Zhou, Ankun; Xia, Chengfeng*Natural Product ReportsDOI:10.1039/d1np00060hPublished: 2022-March (online)https://pubs.rsc.org/en/content/articlelanding/2022/NP/D1NP00060H AbstractCovering up to 2021Complex cyclotryptamine alkaloids with a bispyrrolidino[2,3-b]indoline (BPI) skeleton are an intriguing family of natural ...

Aspulvins A-H, Aspulvinone Analogues with SARS-CoV-2 Mpro Inhibitory and Anti-inflammatory Activities from an Endophytic Cladosporium sp.Liang, Xin-Xin; Zhang, Xing-Jie; Zhao, Ying-Xin; Feng, Jian; Zeng, Jie-Chun; Shi, Qiang-Qiang; Kaunda, Joseph Sakah; Li, Xiao-Li*; Wang, Wei-Guang*; Xiao, Wei-Lie*Journal of Natural ProductsDOI:10.1021/acs.jnatprod.1c01003Published: 2022-Mar-16 (Epub)https://p...

Super-Electron-Donor 2-Azaallyl Anions Enable Construction of IsoquinolinesZi, Quanxing; Li, Minyan; Cong, Jielun; Deng, Guogang; Duan, Shengzu; Yin, Meng; Chen, Wen; Jing, Hong; Yang, Xiaodong*; Walsh, Patrick J*Organic LettersVolume:24 Issue:9 Pages:1786-1790DOI:10.1021/acs.orglett.2c00140Published: 2022-Mar-11https://pubs.acs.org/doi/10.1021/acs.orglett.2c00140AbstractHerein is introduced th...

Identification of Gossypol Acetate as an Autophagy Modulator with Potent Anti-tumor Effect against Cancer CellsCai, Bicheng; Gong, Liang; Zhu, Yiying; Kong, Lingmei; Ju, Xiaoman; Li, Xue; Yang, Xiaodong; Zhou, Hongyu; Li*, Yan*Journal of Agricultural and Food ChemistryVolume:70 Issue:8 Pages:2589-2599DOI:10.1021/acs.jafc.1c06399Published: 2022-Mar-02https://pubs.acs.org/doi/10.1021/acs.jafc.1c0...

Cu-Catalyzed Radical Addition and Oxidation Cascade: Unsymmetrical Trimerization of Indole to Access IsotriazatruxeneDeng, Ting; Yan, Wenxin ; Liu, Xiaoyu ; Hu, Guizhimeng ; Xiao, Weilie*; Mao, Shuai*; Lin, Jun*; Jiao, Yinchun* ; Jin, Yi*ORGANIC LETTERSVolume: 24 Issue: 7 Pages: 1502-1506DOI:10.1021/acs.orglett.2c00180Published: FEB 25 2022https://pubs.acs.org/doi/10.1021/acs.orglett.2c00180 Ab...

Structure units oriented approach towards collective synthesis of sarpagine-ajmaline-koumine type alkaloidsChen, Wen ; Ma, Yonghui ; He, Wenyan ; Wu, Yinxia ; Huang, Yuancheng ; Zhang, Yipeng ; Tian, Hongchang ; WWei, Kai ; Yang, Xiaodong ; Zhang, HongbinNATURE COMMUNICATIONSVolume: 13 Issue: 1 Article Number: 908DOI:10.1038/s41467-022-28535-xPublished: FEB 17 2022https://www.nature.com/article...

Stereoselective gold(I)-catalyzed approach to the synthesis of complex alpha-glycosyl phosphosaccharidesZhang, Xiaojuan; Yang, Yutong; Ding, Jiahao; Zhao, Yun; Zhang, Hongbin; Zhu, Yugen*NATURE COMMUNICATIONSVolume13 Issue1 Article Number421DOI:10.1038/s41467-022-28025-0Published: JAN 20 2022https://www.nature.com/articles/s41467-022-28025-0 AbstractGlycosyl phosphosaccharides represent a large...