Cu-Catalyzed Radical Addition and Oxidation Cascade: Unsymmetrical Trimerization of Indole to Access Isotriazatruxene
Deng, Ting; Yan, Wenxin ; Liu, Xiaoyu ; Hu, Guizhimeng ; Xiao, Weilie*; Mao, Shuai*; Lin, Jun*; Jiao, Yinchun* ; Jin, Yi*
ORGANIC LETTERS
Volume: 24 Issue: 7 Pages: 1502-1506
DOI:10.1021/acs.orglett.2c00180
Published: FEB 25 2022
https://pubs.acs.org/doi/10.1021/acs.orglett.2c00180
Abstract
Herein we describe a Cu-catalyzed radical addition and oxidation cascade reaction for the chemo/regioselective synthesis of unsymmetrical indole trimers (isotriazatruxenes, i-TATs) from easily available starting materials. The i-TATs exhibited blue fluorescence in various solvents with different fluorescence intensities and showed good structural expansibility. A wider range of products could be used in optoelectronic materials by developing suitable derivatives.
