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李明慧 助理研究员

2025年01月09日 14:19  点击:[]

姓名:李明慧

邮箱:liminghui@ynu.edu.cn

职称:助理研究员

地址:云南大学呈贡校区化工楼1501

教育经历:

2020.09-2024.07,北京大学,药剂学,博士

2018.09-2020.07,北京大学,药剂学,硕士

2014.09-2018.07,北京大学,药学,学士

工作经历:

2024.12至今,云南大学药学院/教育部自然资源药物化学重点实验室,助理研究员

2024.07-2024.10,江苏恒瑞医药股份有限公司,制剂中级研究员

研究领域:

1、新型药物递送系统开发

2、基于活性天然产物的创新制剂开发

奖励荣誉:

职教课程与教学成果:

科研项目:

代表性论文:(近五年)

[1] Li M#, Jiang A#, Han H, Chen M, Wang B, Cheng Y, Zhang H, Wang X, Dai W*, Yang W*, Zhang Q*, He B*. A Trinity Nano-Vaccine System with Spatiotemporal Immune Effect for the Adjuvant Cancer Therapy after Radiofrequency Ablation[J]. ACS Nano, 2024,18(5):4590-4612.JCR/中科院1区,IF 15.8

[2] Song G#, Li M#, Fan S#, Qin M, Shao B, Dai W, Zhang H, Wang X, He B*, Zhang Q*. Boosting synergism of chemo- and immuno-therapies via switching paclitaxel-induced apoptosis to mevalonate metabolism-triggered ferroptosis by bisphosphonate coordination lipid nanogranules[J]. Acta Pharmaceutica Sinica B, 2024,14(2):836-853. JCR/中科院1区,IF 14.7

[3] Qin M#, Li M#, Song G, Yang C, Wu P, Dai W, Zhang H, Wang X, Wang Y, Zhou D, He B*, Zhang Q*. Boosting innate and adaptive antitumor immunity via a biocompatible and carrier-free nanovaccine engineered by the bisphosphonates-metal coordination[J]. Nano Today, 2021,37:101097. JCR/中科院1区,IF 13.2

[4] Li M#, Qin M#, Song G, Deng H, Wang D, Wang X, Dai W, He B*, Zhang H*, Zhang Q*. A biomimetic antitumor nanovaccine based on biocompatible calcium pyrophosphate and tumor cell membrane antigens[J]. Asian Journal of Pharmaceutical Sciences, 2021,16(1):97-109. JCR/中科院1区,IF 10.7

[5] Yang L#, Yang Y#, Zhang J, Li M, Yang L, Wang X, Chen M, Zhang H, He B, Wang X, Dai W*, Wang Y*, Zhang Q*. Sequential responsive nano-PROTACs for precise intracellular delivery and enhanced degradation efficacy in colorectal cancer therapy[J]. Signal Transduct Target Ther, 2024,9(1):275. JCR/中科院1区,IF 40.8

[6] Yang A, Sun Y, Lyu B, Chen B, Fan Z, Li M, Zhao Y, Fu J, He B, Zhang H, Wang X, Dai W*, Zhang Q*. One-pot preparation of nanodispersion with readily available components for localized tumor photothermal and photodynamic therapy[J]. Asian J Pharm Sci, 2022,17(1):120-128. JCR/中科院1区,IF 10.7

[7] Qin M, Zhang J, Li M, Yang D, Liu D, Song S, Fu J, Zhang H, Dai W, Wang X, Wang Y, He B*, Zhang Q*. Proteomic analysis of intracellular protein corona of nanoparticles elucidates nano-trafficking network and nano-bio interactions[J]. Theranostics, 2020,10(3):1213-1229. JCR/中科院1区,IF 12.4

 

 

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