Yang QH#, Qin T#, An T, Wu HN, Xu G, Xiang J, Lei KF, Zhang SH, Xia J, Su GF, Wang D, Xue MG, Kong LM, Zhang WX*, Wu S*, Li Y*. Novel PORCN inhibitor WHN-88 targets Wnt/β-catenin pathway and prevents the growth of Wnt-driven cancers. Eur. J. Pharmacol., 2023, 945, 175628
Xiong F#, Kong LM#, Chen L, Xue MG, Cao F, Zhang SQ, Li HM, Yan H, Li Y*, Zuo ZL*. Discovery of potential novel CRBN modulators by virtual screening and bioassay, Eur. J. Med. Chem., 2022, 236, 114355
Zhang SH, Ju XM, Yang QH, ZhuYY, Fan DM, Su GF, Kong LM, Li Y*. USP47 maintains the stemness of colorectal cancer cells and is inhibited by parthenolide. Biochem. Biophys. Res. Commun., 2021, 562:21-28
Li X, Kong LM, Yang QH, Duan AZ, Ju XM, Cai BC, Chen L, An T*, Li Y*. Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth. J. Biol. Chem., 2020, 295: 3576-3589
Ma PC#, An T#, Zhu L, Zhang LL, Wang HS, Ren BY, Sun B, Zhou X, Li Y*, Mao BY*. RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling. Development, 2020, 147, dev188078
Chen L, Fan DM, Tang JW, An T, Li X, Kong LM*, Puno PT*, Li Y*. Discovery of isopenicin A, a meroterpenoid as a novel inhibitor of tubulin polymerization. Biochem. Biophys. Res. Commun., 2020, 525:303-307
Zhu HF#, Wang B#, Kong LM, An T, Li GT, Zhou HY, Gong L, Zhao ZX, Gong YX, Sun HD, Puno PT*, Li Y*. Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin. Cell. Chem. Biol., 2019, 26(8):1122-1132
Zhou HY#, Yu CL#, Kong LM#, Xu XL, Yan JM, Li YC, An T, Gong L, Gong YX, Zhu HF, Zhang HB*, Yang XD*, Li Y*. B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells. Oncogene, 2019, 38:3371-3386
Tang JW#, Kong LM#, Zu WY, Hu K, Su XZ, Li XN, Yan BC, Wang WG, Sun HD, Li Y*, Puno PT*. Isopenicins A–C: Two Types of Novel Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18. Org. Lett., 2019, 21:771-775
Wang LL#, Kong LM#, Liu H, Zhang YQ, Zhang L, Liu XY, Yuan F, Li Y*, Zuo ZL*. Design and synthesis of novel artemisinin derivatives with potent activities against colorectal cancer in vitro and in vivo. Eur. J. Med. Chem., 2019, 182, 111665
An T, Gong YX, Li X, Kong LM, Ma PC, Gong L, Zhu HF, Yu CL, Liu JM, Zhou HY, Mao BY, Li Y*. USP7 inhibitor P5091 inhibits Wnt signaling and coloreal tumor growth. Biochem. Pharmacol., 2017, 131(1):29-39
Yu CL, Gong YX, Zhou HY, Wang M, Kong LM, Liu JM, An T, Zhu HF, Li Y*. Star-PAP, a poly(A) polymerase, functions as a tumor suppressor in an orthpic humanbreast cancer model. Cell. Death. Dis., 2017, 8 (2): e2582.
Shao LD#, Su J#, Ye BX#, Liu JX#, Zuo ZL, Li Y, Wang YY*, Xia CF*, Zhao QS*. Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors. J. Med. Chem., 2017, 60 (21): 9053–9066 60(21).
Zhou HY#, Shang CW#, Wang M, Shen T, Kong LM, Yu CL, Ye ZN, Luo Y, Liu L, Li Y*, Huang SL*. Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK. Biochem. Pharmacol., 2016, 16:39-50
Wang M, Zhou AK, An T, Kong LM, Yu CL, Liu JM, Xia CF*, Zhou HY*, Li Y*. N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells. J. Exp. Clin. Cancer. Res., 2016, 35:41
Kong LM, Mao BY, Zhu HJ*, Li Y*. Novel β-carbolines inhibit Wnt/β-catenin signaling. Cell. Death. Dis., 2015, 6, e1983
